Which types of cancer overexpress the miRNAs measured by OncuraKit?

The three cancer-associated miRNAs used in OncuraKit — miR-21-5p, miR-375-3p, and miR-141-3p — are overexpressed across a broad range of cancer types. miR-21-5p is one of the most universally upregulated oncomiRs and has been documented in virtually every cancer type studied including prostate, breast, colorectal, pancreatic, lung, ovarian, gastric, bladder, and brain cancers. miR-375-3p shows strong overexpression in prostate, esophageal, gastric, pancreatic, and colorectal cancers. miR-141-3p (a member of the miR-200 family) is particularly associated with prostate and colorectal cancer progression. Because these markers are broadly associated with cancer biology rather than organ-specific, the OncuraKit is expected to provide signal across most cancer types — not just the six primary targets.