CLIA-Certified · Laboratory Developed Test

Know before
symptoms start.

OncuraKit screens for 6 cancer types from a single urine sample — using Nobel Prize-winning microRNA science with >97% sensitivity.

No blood draw. No appointment. No waiting room.

100% OnlineHSA / FSA EligibleCLIA-Certified LabNo Blood DrawLaboratory Developed TestNo Prescription Required100% OnlineHSA / FSA EligibleCLIA-Certified LabNo Blood DrawLaboratory Developed TestNo Prescription Required
>97%
Stage I/II Sensitivity
6
Cancer Types Detected
>80,000
Peer-Reviewed Studies
5–7 Days
Results Turnaround
Who OncuraKit Serves

Built for everyone who believes early detection matters.

Whether you're an individual taking charge of your health, a company protecting your team, or a healthcare organization expanding access — OncuraKit meets you where you are.

For Individuals

Take control before symptoms appear.

For adults who want answers — not a waiting room.

  • 1 in 100 adults over 60 are likely to develop cancer
  • Stage I survival rate exceeds 90% for most cancer types
  • No prescription, no appointment, no needles
See if it's right for you
For Employers

Protect your team. Reduce catastrophic costs.

Add OncuraKit to your employee benefits package.

  • Late-stage cancer treatment averages $150,000–$800,000
  • Early detection reduces employer health plan spend by 60%+
  • Bulk pricing and HR reporting available for companies of any size
Explore employer programs
For Healthcare Orgs

Offer patients the most sensitive MCED test available.

Integrate OncuraKit into your patient care pathway.

  • 81–97% Stage I/II sensitivity — highest published among all MCEDs
  • Urine-only: ideal for patients who can't tolerate blood draws
  • CLIA-certified Yenos report with physician interpretation guide
Become a clinical partner
Why It Matters

Early detection changes everything.

When cancer is caught at Stage I or II, most types are highly treatable. By Stage IV, many become nearly impossible to survive. The window between those two realities is where OncuraKit operates.

5-Year Survival Rate: Stage I vs. Stage IV

Source: American Cancer Society, National Cancer Institute

OncuraKit detects microRNA threats before symptoms appear

Colorectal

Stage I — Early0%
Stage IV — Late0%

Pancreatic

Stage I — Early0%
Stage IV — Late0%

Ovarian

Stage I — Early0%
Stage IV — Late0%

Lung

Stage I — Early0%
Stage IV — Late0%

Out of 10 patients diagnosed — who survives?

Colorectal

91%
Caught Early
13%
Caught Late

Pancreatic

44%
Caught Early
3%
Caught Late

Ovarian

93%
Caught Early
31%
Caught Late

Lung

65%
Caught Early
8%
Caught Late
7 in 10

annual cancer deaths occur in cancers with no recommended screening protocol

9 in 10

Americans have postponed health checkups or screenings that could save their lives

Stage I/II

detection gives patients the greatest chance of curative treatment and full recovery

OncuraKit is built specifically to catch cancer at Stage I and II — the stages where lives are most often saved.

Simple Process

Order. Collect. Ship. Done.

From your couch to our California lab — no blood draw, no appointment, no waiting room. Just the clarity you need, in five easy steps.

No blood drawNo doctor's appointmentNo prescriptionNo clinic visitNo waiting room
01
Order Your Kit

Order online

2 minutes

Visit Oncura.health, complete a simple checkout — no prescription, no appointment. Your kit ships that day.

02
OncuraKit

Kit arrives

2–3 days

Your OncuraKit ships in discreet plain packaging directly to your home with everything you need, including a pre-paid return label.

03
SimpleInstructionsSPECIMEN

Collect at home

5 minutes

Use the included collection cup to provide a simple urine sample. No blood draw. No needles. No clinic. No awkward appointments.

04
OncuraKitPRE-PAID RETURN🏥El DoradoHills, CA

Ship to our lab

Pre-paid overnight

Seal your sample in the included bio-safe mailer and drop it in any USPS or FedEx box. Pre-paid overnight shipping to Yenos Analytical in El Dorado Hills, CA.

05
YOUR RESULTSWITHIN NORMAL RANGEmiR-2193%miR-37582%miR-14197%

Get your results

5–7 days

Receive a secure, detailed digital report in your private dashboard — a clear result for each of the 6 cancer types screened.

🏥
El Dorado Hills, CA

Processed at Yenos Analytical — CLIA-Certified

Your sample travels via pre-paid overnight shipping to Yenos Analytical LLC in El Dorado Hills, California. Founded by Dr. Anastassia Kanavarioti (UC Santa Cruz), the CLIA-certified lab uses the MinION/Yenos nanopore platform to analyze your specimen — the same technology behind 4 published peer-reviewed studies. Results are ready in 5–7 days.

CLIA CertifiedPre-Paid Return5–7 Day Results

HSA/FSA eligible · Ships in 1 business day · Pre-paid return included

Spread the word

The kind of thing you text someone you actually care about.

Early detection is a conversation. Be the one who starts it.

M

Mom

iMessage

hey did you see that thing about the urine cancer test? no needles or anything
I actually just ordered one for myself. took like 5 minutes online
wait seriously? which one
OncuraKit. it's $995, covers 6 types. you just pee in a cup and mail it back 😅
ok that's actually wild. no appointment?
nope. shipped to my door. I figure if something shows up early it's way better than stage 4 😬
iMessage

Know someone who should be screened? Forward them the link.

Inside the Lab

How detection actually works

The Yenos MinION/Yenos platform measures three validated miRNA cancer biomarkers — miR-21, miR-375, and miR-141 — in a single urine sample. Every healthy person shares the same baseline (1.0 HL). Cancer shifts that to 1.83 HL, with zero overlap between populations.

Biomarker Signal Threshold

Cancer samples express miR-21, miR-375 & miR-141 at 1.83× the healthy level. Threshold is 1.5×. Zero data overlap confirmed (p=1.6×10⁻²²)

Cell-Level miRNA Dysregulation

MicroRNA dysregulation drives abnormal cell growth, differentiation, and apoptosis — the biological basis for all six cancer types detected.

MinION/Yenos Nanopore Platform

2048-nanopore array with 180 pA baseline current. Osmium-tagged probes bind target miRNA; each molecule blocks ion flow — single-molecule detection, amplification-free.

Published Per-Marker Accuracy

Three validated cancer miRNAs: miR-21 (93.8%), miR-375 (81.5%), miR-141 (97.3%). miR-15b serves as internal control (not a cancer marker).

LIVE · Biomarker Signal
miR-21 · miR-375 · miR-141
1.0 HL1.5 HL threshold1.83×HL
Cancer threshold: 1.5 HLCancer samples: 1.83 HL · p=1.6×10⁻²²Zero data overlap
Cell Morphology — miRNA Dysregulation
HEALTHY · 1.04 HL
Normal miRNA · No flag
CANCER · 1.83 HL
Overexpressed miRNA · Flagged
MinION/Yenos Platform · Nanopore
2048 pores · 180 pA
Buffer/salt (+)Buffer/salt (−)NANOPOREΔI: 180pA → blockedOs-tagged probe+V−V
Normal miRNA (≤1.5 HL) Cancer miRNA (>1.5 HL → 1.83 HL)
Validated miRNA Panel · Yenos 2025
miR-21-5pMulti-cancer
93.8%30/32
miR-375-3pMulti-cancer
81.5%22/27
miR-141-3pMulti-cancer
97.3%36/37
miR-15b-5pControl (not cancer marker)
93.3%28/30
▲ 80% performance threshold

Source: Rafiq & Kanavarioti, Int. J. Mol. Sci. 2025, 26, 3822 · doi:10.3390/ijms26083822

Visualizations are illustrative representations of published analytical methods from Yenos Analytical LLC. Data sourced from Rafiq & Kanavarioti (2025), Kanavarioti et al. (2024, 2022, 2020). Actual lab instrumentation and numerical outputs may vary. OncuraKit is a Laboratory Developed Test (LDT) analyzed by Yenos Analytical, a CLIA-certified laboratory.

How We Compare

No other MCED test matches this.

Every competing multi-cancer early detection (MCED) test requires blood. Most rely on probabilistic scoring that produces data overlap between cancer and healthy patients. OncuraKit is the only test that delivers a clear YES or NO result from a urine sample, with the highest published Stage I/II sensitivity.

Galleri

Grail Corp

Shield MCD

Guardant Health

CancerGuard

Exact Sciences

Yenos / OncuraKit

Yenos Analytical

Sample type
Blood only
Blood only
Blood only
Blood or urine
Cancer types
50
8
8
6 (incl. brain)
Stage I/II sensitivity
16.8% / 40.4%
59.7% overall
20% / 53%
81–97%
Specificity
>99.5%
98.6%
>99%
97% (1 test) / >99.9% (2 tests)
Amplification required
Yes
Yes
Yes
No — single molecule, direct
Data overlap (cancer vs healthy)
Yes — score-based
Yes — score-based
Yes — score-based
Zero (p=1.6×10⁻²²)
Result type
Score / probability
Score / probability
Score / probability
YES or NO

Competitor data sourced from Yenos Analytical LLC presentation, January 2026, citing publicly available company pricing and published clinical validation studies. Galleri (Grail Corp), Shield MCD (Guardant Health), CancerGuard (Exact Sciences/Abbott). Prices and performance metrics subject to change.

What Happens Next

What success looks like at every outcome.

No matter what your result is, you'll have a clear path forward — and you won't face it alone.

Outcome A

Normal Result

miR-21-5p1.02× HL — Normal
miR-375-3p0.98× HL — Normal
miR-141-3p1.11× HL — Normal

All markers below 1.5× HL threshold · No overexpression detected

  • Clear result — within normal range

    All three markers are below the 1.5× healthy level threshold. Your body is expressing miR-21, miR-375, and miR-141 in the expected range.

  • Documented health baseline

    Your results are stored securely in your OncuraKit dashboard — a timestamped baseline for annual comparison and peace of mind.

  • Annual re-screening recommended

    We recommend annual screening starting at 60+, or sooner if you receive an inconclusive mammogram, PSA test, or colonoscopy.

Outcome B

Elevated Result

miR-21-5p1.91× HL — Elevated ↑
miR-375-3p1.78× HL — Elevated ↑
miR-141-3p1.85× HL — Elevated ↑

Above 1.5× HL threshold · Second confirmatory test recommended

  • Receive your detailed report

    Your Yenos lab report shows exact HL scores for each of the three miRNA markers, with a clear Elevated or Normal classification for each.

  • We connect you with a clinician

    OncuraKit provides a complimentary physician consultation to walk through your results and recommend appropriate next steps.

  • Your doctor guides follow-up testing

    A positive screen is not a diagnosis. It means a target-specific clinical evaluation is warranted. Most follow-up tests are covered by insurance.

Remember: An elevated result is not a cancer diagnosis. It is a signal to investigate further — and finding it early, before symptoms, is exactly why you tested. Early-stage cancers detected before spread are 5× more survivable than late-stage diagnoses.

Our Mission

What we believe

OncuraKit exists because we believe early cancer detection shouldn't require a specialist referral, a hospital visit, or even a blood draw. It should be as simple as mailing a letter.

We believe prevention is healthcare

Most cancers detected late are survivable when caught early. We built OncuraKit to shift the conversation from treatment to prevention — putting a powerful screening tool directly in your hands.

We believe science should be accessible

Nobel Prize-winning microRNA research has existed for decades. OncuraKit brings that science out of academic journals and into your home — as a simple, at-home urine test with no clinic visit required.

We believe our test can save lives

While no test can guarantee outcomes, we firmly believe that OncuraKit's >97% sensitivity and specificity — validated in Stage I/II cancer patients — provides the kind of early signal that changes treatment trajectories and saves lives.

We believe the time to test is now

Cancer does not wait for symptoms to appear. By the time most cancers are felt or seen, they are already at an advanced stage. Proactive, annual screening is the only way to stay ahead of it.

OncuraKit is a Laboratory Developed Test (LDT). It is not intended to diagnose, treat, cure, or prevent any disease. Results should be reviewed with a qualified healthcare provider. Early detection reduces risk but does not guarantee outcomes.

Patients and healthcare professionals

Ready to take the next step in your health?

Join thousands who've chosen proactive screening. Order your OncuraKit today — private, simple, and backed by Nobel Prize-winning science.