What step-by-step process does Yenos follow when they receive my sample?

When your specimen arrives at Yenos Analytical in El Dorado Hills, California, the lab follows this process: (1) Sample receipt and chain-of-custody verification — your sample is logged, your specimen ID is confirmed, and the bio-safe mailer seal is inspected; (2) Sample acceptance review — total RNA content is assessed to ensure sufficient material for analysis; (3) RNA extraction — miRNA is isolated from the urine sample using a standardized protocol; (4) Osmium tagging — the three cancer miRNA targets and the internal control are tagged with Yenos osmium metalorganic probes; (5) Nanopore analysis — the tagged sample is loaded onto a MinION flow cell and run for the measurement period; (6) Data analysis and QC — the bioinformatics pipeline processes the current trace data, the bracketing protocol confirms accuracy, and the internal control is verified; (7) Confirmatory testing — any elevated result triggers a second independent run; (8) Report generation — a licensed laboratory scientist reviews and approves the report; (9) Secure delivery — the report is uploaded to your private OncuraKit dashboard.