What is the error rate of the Yenos nanopore miRNA quantification?

The Yenos nanopore platform is designed for quantification rather than sequencing, so 'error rate' is measured differently. The relevant measure is the coefficient of variation (CV) — the variability in repeated measurements of the same sample. Yenos's published data (2024, Non-Coding RNA) reports a relative standard deviation (RSD) of 0.09 for cancer samples (mean 1.83× HL) and 0.17 for healthy samples (mean 1.04× HL). An RSD of 0.09 means the measurement varies by approximately 9% around the mean — which is excellent precision for a clinical molecular assay and, critically, is narrow enough that cancer and healthy distributions do not overlap. PCR-based assays typically show much higher RSD due to amplification variation.