Does sexual activity before collection affect results?

There is no published evidence that sexual activity affects circulating miRNA levels at the HL threshold used by OncuraKit. Sexual activity can cause short-term changes in urethral flora and add cellular material from the urethra and reproductive tract, but these are minimized by the mid-stream collection technique (which discards the initial flow containing urethral material). If you have recently had sexual intercourse, waiting a few hours and collecting a mid-stream sample with proper hygiene is recommended. For men, ejaculation can introduce prostatic and seminal fluid components into the urethra — waiting 30 minutes after ejaculation before collection is a reasonable precaution for men specifically.