How does repeat annual testing improve cancer detection over time?

Annual repeat testing has compounding benefits for cancer detection. First, it establishes a personal baseline — if your miRNA levels are consistently at 1.1× HL annually, a subsequent rise to 1.4× HL (still below the threshold) can be noticed by your physician even before it crosses the threshold. Second, it catches cancers that may have been too early to produce a signal in a prior test — a Stage I cancer in its very earliest days may produce an insufficient signal, but three months or a year later it may cross the threshold at a still-surgically-curable stage. Third, regular testing builds the habit of proactive screening and ongoing engagement with preventive health. Yenos recommends annual re-testing for all adults over 60 regardless of prior results.