What is the positive predictive value (PPV) of OncuraKit?

Positive predictive value (PPV) is the probability that a person who tests positive (elevated) actually has cancer. PPV depends not just on the test's sensitivity and specificity, but also on the prevalence of cancer in the tested population. In a population of adults over 60 (approximately 1% cancer prevalence), OncuraKit's PPV with the two-test confirmatory protocol (>99.9% specificity, ~95% combined sensitivity) is approximately 90%+ — meaning 9 out of 10 people with a confirmed elevated result are likely to have cancer detectable by follow-up. In a lower-risk population (e.g., 40-year-olds with 0.1% cancer prevalence), PPV would be lower. This is one reason why targeting the test to higher-risk populations (adults 60+, those with family history or inconclusive traditional screenings) maximizes clinical utility.