What is the negative predictive value (NPV) of OncuraKit?

Negative predictive value (NPV) is the probability that a person who tests normal (not elevated) actually does not have cancer. In a population with 1% cancer prevalence (adults 60+), OncuraKit's NPV with ~95% combined sensitivity is approximately 99.9% — meaning 999 of 1,000 people with a normal result truly do not have cancer detectable by this test at this time. NPV is generally very high for cancer screening tests used in populations with relatively low cancer prevalence. A normal OncuraKit result provides strong reassurance that the three cancer-associated miRNA markers are not elevated at this time — but does not eliminate cancer risk entirely, since no test has 100% sensitivity. Regular follow-up and adherence to standard-of-care screenings remain important even after a normal result.